Capcom empties its vault for the second time in this updated Wii version of the 2002 GameCube title Resident Evil 0, which was set before the events in the original Resident Evil. Instead of playing as two separate characters in slightly divergent storylines, players now control two characters at once, switching between them at will to solve puzzles and to fight enemies. The female protagonist is Rebecca Chambers, member of the S.T.A.R.S. Bravo Team that would later be sent to Raccoon City to investigate a mysterious disappearance. Former Navy SEAL Billy Coen, a convicted murderer awaiting his sentence, joins her on a train to S.T.A.R.S. headquarters, but things take a turn for the worse when the train is suddenly attacked by zombies.
Players can examine their surroundings, use tools, pick up and combine items to solve puzzles, and fire weapons to stave off the advancing monsters and beasts. The partner system has players controlling one primary character and the computer controlling the other, or guiding both at the same time by simultaneously using the Wii Remote and Nunchuk. Computer-controlled characters can be given the command to attack or to remain idle, conserving bullets when necessary. Acquired items can be swapped between characters when they are together in the same room, and partners can also split off to investigate certain situations alone, keeping the other informed using walkie-talkies.
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